From 2000 to 2001 Mount had a recurring role on the series Third Watch. He starred as Roy Ravelle from 2003 to 2004 on the TV series Line of Fire and as Will Carver on The Mountain from 2004 to 2005. In 2006 Anson starred as Jim Steele in the series Conviction. His best known role started in 2011 playing Cullen Bohannon on the AMC series Hell on Wheels. Mount has also starred in the movies Tully, Urban Legends: Final Cut, Crossroads, Poolhall Junkies, City by the Sea, The Battle of Shaker Heights, In Her Shoes, Walk the Talk, Hick, Straw Dogs, Safe, Non-Stop, and Supremacy. In 2002 Mount was nominated for a Teen Choice Award for Crossroads and he was also nominated for a Razzie Award for Worst Screen Couple with Britney Spears.