She also had a recurring role as Leila Stilwell in the television series Big Love in 2010. She is scheduled to star in the upcoming 2015 film Crawlspace. Upham won awards from the Alliance of Women Film Journalists, American Indian Film Festival, Capri, Hollywood, and the Hollywood Film Festival. Upham left her sister’s apartment in October 2014 on the Muckleshoot Reservation and had not been heard from a week later. On October 16, 2014 Misty Upham’s body was found at the bottom of a cliff in a wooded area.