One of his best known roles came starring as Mickey Milkovich on the TV series Shameless from 2011 to 2016. Fisher voiced the role of Michelangelo in the movies Teenage Mutant Ninja Turtles and Teenage Mutant Ninja Turtles: Out of the Shadows. He has also appeared in the films Freddy Got Fingered, Final Destination 2, Agent Cody Banks, Battle Los Angeles, The Twilight Saga: Breaking Dawn – Part 2, and more. Fisher has been nominated for two Gemini Awards, a Behind the Voice Actors Award, and a Kids’ Choice Award. He has been engaged to actress Layla Alizada since 2014. They married in 2017.