Bryant also participated in the 2008 Senior Bowl, playing for the South team. He recovered a fumble in a narrow South win. After graduating, Bryant was drafted by the Seattle Seahawks with the 121st pick (4th round) of the 2008 NFL Draft. In his rookie season, he was inactive for 12 games, recording just eight tackles. He played sparingly during the 2009 season and was moved to defensive end during the 2010 offseason. He missed over half of the season due to injury and was placed on injured reserve. In 2011, Bryant blocked four kicks, breaking the franchise single-season record. He also had an interception returned for a touchdown in a game against the Chicago Bears. He resigned with the Seattle Seahawks in 2012, inking a five year, $35 million deal.