Penn also served as executive producer for the series Alphas and the TV series Ozzy & Drix from 2003 to 2004. He also produced the films Osmosis Jones, Incident at Loch ness, and The Grand. Penn directed the movies Incident and Loch Ness and The Grand. As an actor he has starred in the movies Politically Correct Party Animals, Star Maps, Chuck & Buck, and Osmosis Jones. In 2004 he was nominated for a Daytime Emmy Award for Ozzy & Drix.